EXAMINE THIS REPORT ON LSD CRYSTAL

Inside the LSD-bound crystal structure, the facet chain of the lid residue L209EL2 varieties intensive hydrophobic contacts with the two LSD and surrounding residues in TMs III, IV, and V (Determine 4C). When the lid moved aside to show the binding pocket in simulation, various of such contacts broke. We Hence hypothesized that L209EL2 functions fo